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Transcriptome profiling of Ewing sarcomas – treatment resistance pathways and IGF‐dependency

Ewing sarcomas (ESs) are aggressive sarcomas driven by EWS fusion genes. We sought to investigate whether whole‐transcriptome sequencing (RNA‐seq) could be used to detect patterns associated with chemotherapy response or tumor progression after first‐line treatment. Transcriptome sequencing (RNA‐seq...

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Detalles Bibliográficos
Autores principales: Chen, Yi, Hesla, Asle C., Lin, Yingbo, Ghaderi, Mehran, Liu, Mingzhi, Yang, Chen, Zhang, Yifan, Tsagkozis, Panagiotis, Larsson, Olle, Haglund, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191197/
https://www.ncbi.nlm.nih.gov/pubmed/32115849
http://dx.doi.org/10.1002/1878-0261.12655