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TRAF4 acts as a fate checkpoint to regulate the adipogenic differentiation of MSCs by activating PKM2
BACKGROUND: Mesenchymal stem cells (MSCs) selectively differentiate into adipocytes or osteoblasts, and several molecules control the fate determination of MSCs. Understanding these key checkpoints greatly contributes to the ability to induce specific MSC differentiation for clinical applications. I...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191261/ https://www.ncbi.nlm.nih.gov/pubmed/32268273 http://dx.doi.org/10.1016/j.ebiom.2020.102722 |