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TRAF4 acts as a fate checkpoint to regulate the adipogenic differentiation of MSCs by activating PKM2

BACKGROUND: Mesenchymal stem cells (MSCs) selectively differentiate into adipocytes or osteoblasts, and several molecules control the fate determination of MSCs. Understanding these key checkpoints greatly contributes to the ability to induce specific MSC differentiation for clinical applications. I...

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Detalles Bibliográficos
Autores principales: Cen, Shuizhong, Li, Jinteng, Cai, Zhaopeng, Pan, Yiqian, Sun, Zehang, Li, Zhaofeng, Ye, Guiwen, Zheng, Guan, Li, Ming, Liu, Wenjie, Yu, Wenhui, Wang, Shan, Xie, Zhongyu, Wang, Peng, Shen, Huiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191261/
https://www.ncbi.nlm.nih.gov/pubmed/32268273
http://dx.doi.org/10.1016/j.ebiom.2020.102722