Chemerin/CMKLR1 Axis Promotes Inflammation and Pyroptosis by Activating NLRP3 Inflammasome in Diabetic Cardiomyopathy Rat

Chemerin and its receptor CMKLR1 (a G-protein-coupled receptor) are inducers of inflammation, and play an important role in diabetic cardiomyopathy (DCM). In this study, we investigated the role of the chemerin/CMKLR1 axis in mediating inflammation and cell death in DCM. Sprague–Dawley rats, treated...

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Detalles Bibliográficos
Autores principales: Xie, Yebin, Huang, Yu, Ling, Xiaoyu, Qin, Haiou, Wang, Min, Luo, Beibei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191320/
https://www.ncbi.nlm.nih.gov/pubmed/32390873
http://dx.doi.org/10.3389/fphys.2020.00381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191320/
https://www.ncbi.nlm.nih.gov/pubmed/32390873
http://dx.doi.org/10.3389/fphys.2020.00381

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