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Downregulation of OSR1 Promotes Colon Adenocarcinoma Progression via FAK-Mediated Akt and MAPK Signaling

INTRODUCTION: Odd-skipped related transcription factor 1 (OSR1) is a newly identified tumor suppressor in many tumor types. However, the role and mechanism of OSR1 in colon adenocarcinoma (COAD) remain unknown. METHODS: OSR1 expression was detected in COAD tissues and cells. COAD cells with OSR1 ove...

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Detalles Bibliográficos
Autores principales: Zhang, Fang, Jiang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191353/
https://www.ncbi.nlm.nih.gov/pubmed/32425550
http://dx.doi.org/10.2147/OTT.S242386