Metformin Ameliorates Aβ Pathology by Insulin-Degrading Enzyme in a Transgenic Mouse Model of Alzheimer's Disease

Alzheimer's disease (AD) is the most common neurodegenerative disease. The accumulation of amyloid beta (Aβ) is the main pathology of AD. Metformin, a well-known antidiabetic drug, has been reported to have AD-protective effect. However, the mechanism is still unclear. In this study, we tried t...

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Detalles Bibliográficos
Autores principales: Lu, Xin-Yi, Huang, Shun, Chen, Qu-Bo, Zhang, Dapeng, Li, Wanyan, Ao, Ran, Leung, Feona Chung-Yin, Zhang, Zhimin, Huang, Jisheng, Tang, Ying, Zhang, Shi-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191377/
https://www.ncbi.nlm.nih.gov/pubmed/32377293
http://dx.doi.org/10.1155/2020/2315106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191377/
https://www.ncbi.nlm.nih.gov/pubmed/32377293
http://dx.doi.org/10.1155/2020/2315106

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