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Adipose-derived exosomes protect the pulmonary endothelial barrier in ventilator-induced lung injury by inhibiting the TRPV4/Ca(2+) signaling pathway

Mechanical ventilation (MV) is the main supportive treatment of acute respiratory distress syndrome (ARDS), but it may lead to ventilator-induced lung injury (VILI). Large epidemiological studies have found that obesity was associated with lower mortality in mechanically ventilated patients with acu...

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Detalles Bibliográficos
Autores principales: Yu, Qian, Wang, Daoxin, Wen, Xiaoting, Tang, Xumao, Qi, Di, He, Jing, Zhao, Yan, Deng, Wang, Zhu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191475/
https://www.ncbi.nlm.nih.gov/pubmed/32073873
http://dx.doi.org/10.1152/ajplung.00255.2019