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Polymorphic Region-Specific Antibody for Evaluation of Affinity-Associated Profile of Chimeric Antigen Receptor

Antibody applications in cancer immunotherapy involve diverse strategies, some of which redirect T cell-mediated immunity via engineered antibodies. Affinity is a trait that is crucial for these strategies, as optimal affinity reduces unwanted side effects while retaining therapeutic function. Antib...

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Detalles Bibliográficos
Autores principales: Han, Chungyong, Choi, Beom K., Kim, Seon-Hee, Sim, Su-Jung, Han, Seongeun, Park, Bomi, Tsuchiya, Yohei, Takahashi, Masaki, Kim, Young H., Eom, Hyeon-Seok, Kitaguchi, Tetsuya, Ueda, Hiroshi, Kwon, Byoung S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191539/
https://www.ncbi.nlm.nih.gov/pubmed/32368617
http://dx.doi.org/10.1016/j.omto.2020.04.004