Computational Studies on the Mechanisms of Nonenzymatic Intramolecular Cyclization of the Glutamine Residues Located at N-Termini Catalyzed by Inorganic Phosphate Species

[Image: see text] Glutamine (Gln) residues located at N-termini undergo spontaneous intramolecular cyclization, causing the formation of pyroglutamic acid (pGlu) residues. pGlu residues have been detected at the N-termini in various peptides and proteins. The formation of pGlu residues during the fe...

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Detalles Bibliográficos
Autores principales: Nakayoshi, Tomoki, Kato, Koichi, Kurimoto, Eiji, Oda, Akifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191561/
https://www.ncbi.nlm.nih.gov/pubmed/32363268
http://dx.doi.org/10.1021/acsomega.9b04384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191561/
https://www.ncbi.nlm.nih.gov/pubmed/32363268
http://dx.doi.org/10.1021/acsomega.9b04384

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