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Real-time monitoring of cAMP in brown adipocytes reveals differential compartmentation of β(1) and β(3)-adrenoceptor signalling
OBJECTIVE: 3′,5′-Cyclic adenosine monophosphate (cAMP) is a central second messenger governing brown adipocyte differentiation and function. β-adrenergic receptors (β-ARs) stimulate adenylate cyclases which produce cAMP. Moreover, cyclic nucleotide levels are tightly controlled by phosphodiesterases...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191645/ https://www.ncbi.nlm.nih.gov/pubmed/32247064 http://dx.doi.org/10.1016/j.molmet.2020.100986 |