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Real-time monitoring of cAMP in brown adipocytes reveals differential compartmentation of β(1) and β(3)-adrenoceptor signalling

OBJECTIVE: 3′,5′-Cyclic adenosine monophosphate (cAMP) is a central second messenger governing brown adipocyte differentiation and function. β-adrenergic receptors (β-ARs) stimulate adenylate cyclases which produce cAMP. Moreover, cyclic nucleotide levels are tightly controlled by phosphodiesterases...

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Detalles Bibliográficos
Autores principales:	Kannabiran, Sukanya Arcot, Gosejacob, Dominic, Niemann, Birte, Nikolaev, Viacheslav O., Pfeifer, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191645/ https://www.ncbi.nlm.nih.gov/pubmed/32247064 http://dx.doi.org/10.1016/j.molmet.2020.100986

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