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IP(3)-Dependent Ca(2+) Oscillations Switch into a Dual Oscillator Mechanism in the Presence of PLC-Linked Hormones
Ca(2+) oscillations that depend on inositol-1,4,5-trisphosphate (IP(3)) have been ascribed to biphasic Ca(2+) regulation of the IP(3) receptor (IP(3)R) or feedback mechanisms controlling IP(3) levels in different cell types. IP(3) uncaging in hepatocytes elicits Ca(2+) transients that are often loca...
Autores principales: | Bartlett, Paula J., Cloete, Ielyaas, Sneyd, James, Thomas, Andrew P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191650/ https://www.ncbi.nlm.nih.gov/pubmed/32353764 http://dx.doi.org/10.1016/j.isci.2020.101062 |
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