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Accurate confidence intervals for risk difference in meta-analysis with rare events
BACKGROUND: Meta-analysis provides a useful statistical tool to effectively estimate treatment effect from multiple studies. When the outcome is binary and it is rare (e.g., safety data in clinical trials), the traditionally used methods may have unsatisfactory performance. METHODS: We propose using...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191692/ https://www.ncbi.nlm.nih.gov/pubmed/32349702 http://dx.doi.org/10.1186/s12874-020-00954-8 |