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Accurate confidence intervals for risk difference in meta-analysis with rare events

BACKGROUND: Meta-analysis provides a useful statistical tool to effectively estimate treatment effect from multiple studies. When the outcome is binary and it is rare (e.g., safety data in clinical trials), the traditionally used methods may have unsatisfactory performance. METHODS: We propose using...

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Detalles Bibliográficos
Autores principales: Jiang, Tao, Cao, Baixin, Shan, Guogen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191692/
https://www.ncbi.nlm.nih.gov/pubmed/32349702
http://dx.doi.org/10.1186/s12874-020-00954-8