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l-Carnitine conjugated chitosan-stearic acid polymeric micelles for improving the oral bioavailability of paclitaxel

A delivery system based on l-carnitine (LC) conjugated chitosan (CS)-stearic acid polymeric micelles has been developed for improving the oral bioavailability of paclitaxel (PTX) through targeting intestinal organic cation/carnitine transporter 2 (OCTN2). Stearic acid grafted chitosan (CS-SA), as mi...

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Detalles Bibliográficos
Autores principales: Yang, Tan, Feng, Jianfang, Zhang, Qian, Wu, Wei, Mo, Hailan, Huang, Lanzhen, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191914/
https://www.ncbi.nlm.nih.gov/pubmed/32306775
http://dx.doi.org/10.1080/10717544.2020.1748762