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Sitagliptin Inhibits Extracellular Matrix Accumulation and Proliferation in Lung Fibroblasts

BACKGROUND: Fibroblasts activation-induced fibrosis can cause idiopathic pulmonary fibrosis (IPF). Excessive activation of fibroblasts contributes to poor healing or severe visceral fibrosis and even organ dysfunction. Sitagliptin acts as a dipeptidyl peptidase 4 inhibitor to reduce glucose level in...

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Detalles Bibliográficos
Autores principales: Liu, Xiuwu, Zhang, Tao, Zhang, Chengcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7191949/
https://www.ncbi.nlm.nih.gov/pubmed/32301442
http://dx.doi.org/10.12659/MSM.922644