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A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling

Interleukin-1β (IL-1β) is a key orchestrator of anti-microbial immunity whose secretion is typically dependent on activation of inflammasomes. However, many pathogens have evolved strategies to evade inflammasome activation. Here we describe an alternative, two-cell model for IL-1β release where inv...

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Detalles Bibliográficos
Autores principales: Donado, Carlos A., Cao, Anh B., Simmons, Daimon P., Croker, Ben A., Brennan, Patrick J., Brenner, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192215/
https://www.ncbi.nlm.nih.gov/pubmed/32268091
http://dx.doi.org/10.1016/j.celrep.2020.03.030