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A Two-Cell Model for IL-1β Release Mediated by Death-Receptor Signaling
Interleukin-1β (IL-1β) is a key orchestrator of anti-microbial immunity whose secretion is typically dependent on activation of inflammasomes. However, many pathogens have evolved strategies to evade inflammasome activation. Here we describe an alternative, two-cell model for IL-1β release where inv...
Autores principales: | Donado, Carlos A., Cao, Anh B., Simmons, Daimon P., Croker, Ben A., Brennan, Patrick J., Brenner, Michael B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192215/ https://www.ncbi.nlm.nih.gov/pubmed/32268091 http://dx.doi.org/10.1016/j.celrep.2020.03.030 |
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