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Evolutionary innovation using EDGE, a system for localized elevated mutagenesis

Mutations arising across the whole genome can hinder the emergence of evolutionary innovation required for adaptation because many mutations are deleterious. This trade-off is overcome by elevated mutagenesis to localized loci. Examples include phase variation and diversity-generating retroelements....

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Detalles Bibliográficos
Autores principales: Yi, Xiao, Kazlauskas, Romas, Travisano, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192385/
https://www.ncbi.nlm.nih.gov/pubmed/32353078
http://dx.doi.org/10.1371/journal.pone.0232330