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Placental defects lead to embryonic lethality in mice lacking the Formin and PCP proteins Daam1 and Daam2

The actin cytoskeleton plays a central role in establishing cell polarity and shape during embryonic morphogenesis. Daam1, a member of the Formin family of actin cytoskeleton regulators, is a Dvl2-binding protein that functions in the Wnt/Planar Cell Polarity (PCP) pathway. To examine the role of th...

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Detalles Bibliográficos
Autores principales: Nakaya, Masa-aki, Gudmundsson, Kristibjorn Orri, Komiya, Yuko, Keller, Jonathan R., Habas, Raymond, Yamaguchi, Terry P., Ajima, Rieko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192421/
https://www.ncbi.nlm.nih.gov/pubmed/32353019
http://dx.doi.org/10.1371/journal.pone.0232025