Placental transfer of Letermovir & Maribavir in the ex vivo human cotyledon perfusion model. New perspectives for in utero treatment of congenital cytomegalovirus infection

BACKGROUND: Congenital cytomegalovirus infection can lead to severe sequelae. When fetal infection is confirmed, we hypothesize that fetal treatment could improve the outcome. Maternal oral administration of an effective drug crossing the placenta could allow fetal treatment. Letermovir (LMV) and Ma...

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Detalles Bibliográficos
Autores principales: Faure Bardon, Valentine, Peytavin, Gilles, Lê, Minh Patrick, Guilleminot, Tiffany, Elefant, Elisabeth, Stirnemann, Julien, Leruez-Ville, Marianne, Ville, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192425/
https://www.ncbi.nlm.nih.gov/pubmed/32353010
http://dx.doi.org/10.1371/journal.pone.0232140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192425/
https://www.ncbi.nlm.nih.gov/pubmed/32353010
http://dx.doi.org/10.1371/journal.pone.0232140

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