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Benchmarking RNA-seq differential expression analysis methods using spike-in and simulation data

Benchmarking RNA-seq differential expression analysis methods using spike-in and simulated RNA-seq data has often yielded inconsistent results. The spike-in data, which were generated from the same bulk RNA sample, only represent technical variability, making the test results less reliable. We compa...

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Detalles Bibliográficos
Autores principales: Baik, Bukyung, Yoon, Sora, Nam, Dougu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192453/
https://www.ncbi.nlm.nih.gov/pubmed/32353015
http://dx.doi.org/10.1371/journal.pone.0232271