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Mitochondrial oxidative phosphorylation in peripheral blood mononuclear cells is decreased in chronic HIV and correlates with immune dysregulation

BACKGROUND: Cellular immunometabolism among people living with HIV (PLWH) on antiretroviral therapy (ART) remains under investigated. We assessed the relationships between mitochondrial oxidative phosphorylation (OXPHOS) in peripheral blood mononuclear cells (PBMCs) and blood parameters associated w...

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Detalles Bibliográficos
Autores principales: Gangcuangco, Louie Mar A., Mitchell, Brooks I., Siriwardhana, Chathura, Kohorn, Lindsay B., Chew, Glen M., Bowler, Scott, Kallianpur, Kalpana J., Chow, Dominic C., Ndhlovu, Lishomwa C., Gerschenson, Mariana, Shikuma, Cecilia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192478/
https://www.ncbi.nlm.nih.gov/pubmed/32353005
http://dx.doi.org/10.1371/journal.pone.0231761