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Contribution of STAT1 to innate and adaptive immunity during type I interferon-mediated lethal virus infection

Signal transducers and activators of transcription (STAT) 1 is critical for cellular responses to type I interferons (IFN-Is), with the capacity to determine the outcome of viral infection. We previously showed that while wildtype (WT) mice develop mild disease and survive infection with lymphocytic...

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Detalles Bibliográficos
Autores principales: Jung, So Ri, Ashhurst, Thomas M., West, Phillip K., Viengkhou, Barney, King, Nicholas J. C., Campbell, Iain L., Hofer, Markus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192509/
https://www.ncbi.nlm.nih.gov/pubmed/32310998
http://dx.doi.org/10.1371/journal.ppat.1008525