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Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13
The emergence of artemisinin (ART) resistance in Plasmodium falciparum intra-erythrocytic parasites has led to increasing treatment failure rates with first-line ART-based combination therapies in Southeast Asia. Decreased parasite susceptibility is caused by K13 mutations, which are associated clin...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192513/ https://www.ncbi.nlm.nih.gov/pubmed/32310999 http://dx.doi.org/10.1371/journal.ppat.1008482 |