Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13

The emergence of artemisinin (ART) resistance in Plasmodium falciparum intra-erythrocytic parasites has led to increasing treatment failure rates with first-line ART-based combination therapies in Southeast Asia. Decreased parasite susceptibility is caused by K13 mutations, which are associated clin...

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Detalles Bibliográficos
Autores principales: Gnädig, Nina F., Stokes, Barbara H., Edwards, Rachel L., Kalantarov, Gavreel F., Heimsch, Kim C., Kuderjavy, Michal, Crane, Audrey, Lee, Marcus C. S., Straimer, Judith, Becker, Katja, Trakht, Ilya N., Odom John, Audrey R., Mok, Sachel, Fidock, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192513/
https://www.ncbi.nlm.nih.gov/pubmed/32310999
http://dx.doi.org/10.1371/journal.ppat.1008482

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