Leveraging gene co-expression patterns to infer trait-relevant tissues in genome-wide association studies

Genome-wide association studies (GWASs) have identified many SNPs associated with various common diseases. Understanding the biological functions of these identified SNP associations requires identifying disease/trait relevant tissues or cell types. Here, we develop a network method, CoCoNet, to fac...

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Detalles Bibliográficos
Autores principales: Shang, Lulu, Smith, Jennifer A., Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192514/
https://www.ncbi.nlm.nih.gov/pubmed/32310941
http://dx.doi.org/10.1371/journal.pgen.1008734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192514/
https://www.ncbi.nlm.nih.gov/pubmed/32310941
http://dx.doi.org/10.1371/journal.pgen.1008734

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