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Leveraging gene co-expression patterns to infer trait-relevant tissues in genome-wide association studies
Genome-wide association studies (GWASs) have identified many SNPs associated with various common diseases. Understanding the biological functions of these identified SNP associations requires identifying disease/trait relevant tissues or cell types. Here, we develop a network method, CoCoNet, to fac...
Autores principales: | Shang, Lulu, Smith, Jennifer A., Zhou, Xiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192514/ https://www.ncbi.nlm.nih.gov/pubmed/32310941 http://dx.doi.org/10.1371/journal.pgen.1008734 |
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