Microfluidic automated plasmid library enrichment for biosynthetic gene cluster discovery

Microbial biosynthetic gene clusters are a valuable source of bioactive molecules. However, because they typically represent a small fraction of genomic material in most metagenomic samples, it remains challenging to deeply sequence them. We present an approach to isolate and sequence gene clusters...

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Detalles Bibliográficos
Autores principales: Xu, Peng, Modavi, Cyrus, Demaree, Benjamin, Twigg, Frederick, Liang, Benjamin, Sun, Chen, Zhang, Wenjun, Abate, Adam R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192590/
https://www.ncbi.nlm.nih.gov/pubmed/32095820
http://dx.doi.org/10.1093/nar/gkaa131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192590/
https://www.ncbi.nlm.nih.gov/pubmed/32095820
http://dx.doi.org/10.1093/nar/gkaa131

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