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Microfluidic automated plasmid library enrichment for biosynthetic gene cluster discovery
Microbial biosynthetic gene clusters are a valuable source of bioactive molecules. However, because they typically represent a small fraction of genomic material in most metagenomic samples, it remains challenging to deeply sequence them. We present an approach to isolate and sequence gene clusters...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192590/ https://www.ncbi.nlm.nih.gov/pubmed/32095820 http://dx.doi.org/10.1093/nar/gkaa131 |