A novel NGS library preparation method to characterize native termini of fragmented DNA

Biological and chemical DNA fragmentation generates DNA molecules with a variety of termini, including blunt ends and single-stranded overhangs. We have developed a Next Generation Sequencing (NGS) assay, XACTLY, to interrogate the termini of fragmented DNA, information traditionally lost in standar...

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Detalles Bibliográficos
Autores principales: Harkins, Kelly M, Schaefer, Nathan K, Troll, Christopher J, Rao, Varsha, Kapp, Joshua, Naughton, Colin, Shapiro, Beth, Green, Richard E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192605/
https://www.ncbi.nlm.nih.gov/pubmed/32112100
http://dx.doi.org/10.1093/nar/gkaa128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192605/
https://www.ncbi.nlm.nih.gov/pubmed/32112100
http://dx.doi.org/10.1093/nar/gkaa128

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