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Long noncoding RNA HCP5 participates in premature ovarian insufficiency by transcriptionally regulating MSH5 and DNA damage repair via YB1

The genetic etiology of premature ovarian insufficiency (POI) has been well established to date, however, the role of long noncoding RNAs (lncRNAs) in POI is largely unknown. In this study, we identified a down-expressed lncRNA HCP5 in granulosa cells (GCs) from biochemical POI (bPOI) patients, whic...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyan, Zhang, Xinyue, Dang, Yujie, Li, Duan, Lu, Gang, Chan, Wai-Yee, Leung, Peter C K, Zhao, Shidou, Qin, Yingying, Chen, Zi-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192606/
https://www.ncbi.nlm.nih.gov/pubmed/32112110
http://dx.doi.org/10.1093/nar/gkaa127