Locally acting transcription factors regulate p53-dependent cis-regulatory element activity

The master tumor suppressor p53 controls transcription of a wide-ranging gene network involved in apoptosis, cell cycle arrest, DNA damage repair, and senescence. Recent studies revealed pervasive binding of p53 to cis-regulatory elements (CREs), which are non-coding segments of DNA that spatially a...

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Detalles Bibliográficos
Autores principales: Catizone, Allison N, Uzunbas, Gizem Karsli, Celadova, Petra, Kuang, Sylvia, Bose, Daniel, Sammons, Morgan A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192610/
https://www.ncbi.nlm.nih.gov/pubmed/32133495
http://dx.doi.org/10.1093/nar/gkaa147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192610/
https://www.ncbi.nlm.nih.gov/pubmed/32133495
http://dx.doi.org/10.1093/nar/gkaa147

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