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Quantitative comparison of within-sample heterogeneity scores for DNA methylation data

DNA methylation is an epigenetic mark with important regulatory roles in cellular identity and can be quantified at base resolution using bisulfite sequencing. Most studies are limited to the average DNA methylation levels of individual CpGs and thus neglect heterogeneity within the profiled cell po...

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Detalles Bibliográficos
Autores principales: Scherer, Michael, Nebel, Almut, Franke, Andre, Walter, Jörn, Lengauer, Thomas, Bock, Christoph, Müller, Fabian, List, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192612/
https://www.ncbi.nlm.nih.gov/pubmed/32103242
http://dx.doi.org/10.1093/nar/gkaa120