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Structure specific recognition of telomeric repeats containing RNA by the RGG-box of hnRNPA1

The telomere repeats containing RNA (TERRA) is transcribed from the C-rich strand of telomere DNA and comprises of UUAGGG nucleotides repeats in humans. The TERRA RNA repeats can exist in single stranded, RNA-DNA hybrid and G-quadruplex forms in the cell. Interaction of TERRA RNA with hnRNPA1 has be...

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Detalles Bibliográficos
Autores principales: Ghosh, Meenakshi, Singh, Mahavir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192615/
https://www.ncbi.nlm.nih.gov/pubmed/32128583
http://dx.doi.org/10.1093/nar/gkaa134