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S3norm: simultaneous normalization of sequencing depth and signal-to-noise ratio in epigenomic data
Quantitative comparison of epigenomic data across multiple cell types or experimental conditions is a promising way to understand the biological functions of epigenetic modifications. However, differences in sequencing depth and signal-to-noise ratios in the data from different experiments can hinde...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192629/ https://www.ncbi.nlm.nih.gov/pubmed/32086521 http://dx.doi.org/10.1093/nar/gkaa105 |