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Pharmacokinetics of single dose sildenafil orally administered in canine models of chronic embolic pulmonary hypertension

Information regarding the pharmacokinetics of oral sildenafil in dogs with pulmonary hypertension is limited. In this study, we examined the pharmacokinetics of oral sildenafil in a canine model of chronic embolic pulmonary hypertension (CEPH). The CEPH model was developed by repeatedly injecting mi...

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Detalles Bibliográficos
Autores principales: AKABANE, Ryota, SATO, Touko, SAKATANI, Atsushi, OGAWA, Mizuki, NAGAKAWA, Masayoshi, MIYAKAWA, Hirosumi, MIYAGAWA, Yuichi, TAZAKI, Hiroyuki, TAKEMURA, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192714/
https://www.ncbi.nlm.nih.gov/pubmed/32101822
http://dx.doi.org/10.1292/jvms.19-0595