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Reblastatins Inhibit Phenotypic Changes of Monocytes/Macrophages in a Milieu Rich in 27-Hydroxycholesterol

We investigated effects of reblastatins on phenotypic changes in monocytes/macrophages induced by 27-hydroxycholesterol (27OHChol). Treatment of THP-1 monocytic cells with reblastatin derivatives, such as 17-demethoxy-reblastatin (17-DR), 18-dehydroxyl-17-demethoxyreblastatin (WK88-1), 18-hydroxyl-1...

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Detalles Bibliográficos
Autores principales: Choi, Jeongyoon, Kim, Bo-Young, Son, Yonghae, Lee, Dongho, Hong, Young-Soo, Kim, Min Su, Kim, Koanhoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192833/
https://www.ncbi.nlm.nih.gov/pubmed/32395369
http://dx.doi.org/10.4110/in.2020.20.e17