Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress

Viral infection during pregnancy is often associated with neuropsychiatric conditions. In mice, exposure of pregnant dams to the viral mimetic poly(I:C), serves as a model that simulates such pathology in the offspring, through a process known as Maternal Immune Activation (MIA). To investigate the...

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Detalles Bibliográficos
Autores principales: Ben-Yehuda, Hila, Matcovitch-Natan, Orit, Kertser, Alexander, Spinrad, Amit, Prinz, Marco, Amit, Ido, Schwartz, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192855/
https://www.ncbi.nlm.nih.gov/pubmed/31772304
http://dx.doi.org/10.1038/s41380-019-0604-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192855/
https://www.ncbi.nlm.nih.gov/pubmed/31772304
http://dx.doi.org/10.1038/s41380-019-0604-0

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