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Rapid lipid bilayer membrane formation on Parylene coated apertures to perform ion channel analyses

We present a chip design allowing rapid and robust lipid bilayer (LBL) membrane formation using a Parylene coated thin silicon nitride aperture. After bilayer formation, single membrane channels can be reconstituted and characterized by electrophysiology. The ability for robust reconstitution will a...

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Detalles Bibliográficos
Autores principales: Ahmed, Tanzir, van den Driesche, Sander, Bafna, Jayesh Arun, Oellers, Martin, Hemmler, Roland, Gall, Karsten, Wagner, Richard, Winterhalter, Mathias, Vellekoop, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192868/
https://www.ncbi.nlm.nih.gov/pubmed/32355998
http://dx.doi.org/10.1007/s10544-020-0473-y