Cargando…

N,N-Dimethylaminopyrene as a fluorescent affinity mass tag for ligand-binding mode analysis

Elucidation of the binding mode of protein–ligand interactions provides insights for the design of new pharmacological tools and drug leads. Specific labeling of target proteins with chemical probes, in which the ligands are conjugated with reacting and detecting groups, can establish the binding po...

Descripción completa

Detalles Bibliográficos
Autores principales: Arai, Atsushi, Watanabe, Rei, Hattori, Atsunori, Iio, Keita, Hu, Yaping, Yoneda, Kozo, Kigoshi, Hideo, Kita, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192892/
https://www.ncbi.nlm.nih.gov/pubmed/32355254
http://dx.doi.org/10.1038/s41598-020-64321-9