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N,N-Dimethylaminopyrene as a fluorescent affinity mass tag for ligand-binding mode analysis
Elucidation of the binding mode of protein–ligand interactions provides insights for the design of new pharmacological tools and drug leads. Specific labeling of target proteins with chemical probes, in which the ligands are conjugated with reacting and detecting groups, can establish the binding po...
Autores principales: | Arai, Atsushi, Watanabe, Rei, Hattori, Atsunori, Iio, Keita, Hu, Yaping, Yoneda, Kozo, Kigoshi, Hideo, Kita, Masaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192892/ https://www.ncbi.nlm.nih.gov/pubmed/32355254 http://dx.doi.org/10.1038/s41598-020-64321-9 |
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