Genomic copy number variation correlates with survival outcomes in WHO grade IV glioma

Allele-specific copy number analysis of tumors (ASCAT) assesses copy number variations (CNV) while accounting for aberrant cell fraction and tumor ploidy. We evaluated if ASCAT-assessed CNV are associated with survival outcomes in 56 patients with WHO grade IV gliomas. Tumor data analyzed by Affymet...

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Detalles Bibliográficos
Autores principales: Buchwald, Zachary S., Tian, Sibo, Rossi, Michael, Smith, Geoffrey H., Switchenko, Jeffrey, Hauenstein, Jennifer E., Moreno, Carlos S., Press, Robert H., Prabhu, Roshan S., Zhong, Jim, Saxe, Debra F., Neill, Stewart G., Olson, Jeffrey J., Crocker, Ian R., Curran, Walter J., Shu, Hui-Kuo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192941/
https://www.ncbi.nlm.nih.gov/pubmed/32355162
http://dx.doi.org/10.1038/s41598-020-63789-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192941/
https://www.ncbi.nlm.nih.gov/pubmed/32355162
http://dx.doi.org/10.1038/s41598-020-63789-9

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