Cargando…

Genomic copy number variation correlates with survival outcomes in WHO grade IV glioma

Allele-specific copy number analysis of tumors (ASCAT) assesses copy number variations (CNV) while accounting for aberrant cell fraction and tumor ploidy. We evaluated if ASCAT-assessed CNV are associated with survival outcomes in 56 patients with WHO grade IV gliomas. Tumor data analyzed by Affymet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Buchwald, Zachary S., Tian, Sibo, Rossi, Michael, Smith, Geoffrey H., Switchenko, Jeffrey, Hauenstein, Jennifer E., Moreno, Carlos S., Press, Robert H., Prabhu, Roshan S., Zhong, Jim, Saxe, Debra F., Neill, Stewart G., Olson, Jeffrey J., Crocker, Ian R., Curran, Walter J., Shu, Hui-Kuo G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192941/ https://www.ncbi.nlm.nih.gov/pubmed/32355162 http://dx.doi.org/10.1038/s41598-020-63789-9

Ejemplares similares

Gliosarcoma: distinct molecular pathways and genomic alterations identified by DNA copy number/SNP microarray analysis
por: Lowder, Lindsey, et al.
Publicado: (2019)

Proton vs. Photon Radiation Therapy for Primary Gliomas: An Analysis of the National Cancer Data Base
por: Jhaveri, Jaymin, et al.
Publicado: (2018)

The Association Between Radiation Therapy Dose and Overall Survival in Patients With Intracranial Infiltrative Low-Grade Glioma Treated With Concurrent and/or Adjuvant Chemotherapy
por: Prabhu, Roshan S., et al.
Publicado: (2020)

Rising Incidence of Mucosal Melanoma of the Head and Neck in the United States
por: Marcus, David M., et al.
Publicado: (2012)

Moderately Hypofractionated Radiation for Benign Meningiomas and Schwannomas: A Report of 70 Patients Treated Between 2008 and 2018
por: Dhere, Vishal R., et al.
Publicado: (2020)

Hypofractionated radiosurgery for intact or resected brain metastases: defining the optimal dose and fractionation
por: Eaton, Bree R, et al.
Publicado: (2013)

Neoadjuvant Hormonal Therapy is Associated with Comparable Outcomes to Neoadjuvant Chemotherapy in Post-Menopausal Women with Estrogen Receptor-Positive Breast Cancer
por: Marcus, David M., et al.
Publicado: (2013)

Immunomodulatory Low-Dose Whole-Lung Radiation for Patients with Coronavirus Disease 2019-Related Pneumonia
por: Hess, Clayton B., et al.
Publicado: (2021)

Leptomeningeal disease and neurologic death after surgical resection and radiosurgery for brain metastases: A multi-institutional analysis
por: Prabhu, Roshan S., et al.
Publicado: (2021)

Prospective International Pilot Study Evaluating the Efficacy of a Self-Guided Contouring Teaching Module With Integrated Feedback for Transitioning From 2D to 3D Treatment Planning
por: Abugideiri, Mustafa, et al.
Publicado: (2019)

Mutation and Copy Number Alterations Analysis of KIF23 in Glioma
por: Zhao, Zheng, et al.
Publicado: (2021)

DNA copy number analysis of Grade II–III and Grade IV gliomas reveals differences in molecular ontogeny including chromothripsis associated with IDH mutation status
por: Cohen, Adam, et al.
Publicado: (2015)

Immune niches in brain metastases contain TCF1+ stem-like T cells, are associated with disease control and are modulated by preoperative SRS
por: Jansen, Caroline S., et al.
Publicado: (2023)

Clinical outcomes of radiotherapy as initial local therapy for Graves’ ophthalmopathy and predictors of the need for post-radiotherapy decompressive surgery
por: Prabhu, Roshan S, et al.
Publicado: (2012)

OR25-2 RBFOX2 Copy Number Variation Disrupts Urethral Development Causing Hypospadias
por: O'Neill, Marisol, et al.
Publicado: (2022)

Definitive intensity modulated proton re-irradiation for lung cancer in the immunotherapy era
por: Janopaul-Naylor, James R., et al.
Publicado: (2023)

Improvement in Quality of Life Following Breast Reconstruction in Patients With Stage IV Metastatic Breast Cancer
por: Hespe, Geoffrey E., et al.
Publicado: (2020)

Effects of a 2-km Swim on Markers of Cycling Performance in Elite Age-Group Triathletes
por: Rothschild, Jeffrey, et al.
Publicado: (2019)

Spatial Distance Correlates With Genetic Distance in Diffuse Glioma
por: Gates, Evan D. H., et al.
Publicado: (2019)

A Systematic Pipeline for the Objective Comparison of Whole-Brain Spectroscopic MRI with Histology in Biopsy Specimens from Grade 3 Glioma
por: Cordova, J. Scott, et al.
Publicado: (2016)

Role of p16 deletion and Bmi1 copy number variation in glioma
por: Chetan, GK, et al.
Publicado: (2014)

Research in collegiate mathematics education IV
por: Dubinsky, Ed, et al.
Publicado: (2001)

Copy number analysis of the low-copy repeats at the primate NPHP1 locus by array comparative genomic hybridization
por: Yuan, Bo, et al.
Publicado: (2016)

Detection of cell‐free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients
por: Mouliere, Florent, et al.
Publicado: (2018)

CINmetrics: an R package for analyzing copy number aberrations as a measure of chromosomal instability
por: Oza, Vishal H., et al.
Publicado: (2023)

Apolipoprotein(a) Kringle-IV Type 2 Copy Number Variation Is Associated with Venous Thromboembolism
por: Sticchi, Elena, et al.
Publicado: (2016)

PCR-Based Simple Subgrouping Is Validated for Classification of Gliomas and Defines Negative Prognostic Copy Number Aberrations in IDH Mutant Gliomas
por: Nakae, Shunsuke, et al.
Publicado: (2015)

Factors Affecting Clinical Outcomes Among Patients Infected With HIV and Anal Cancer Treated With Modern Definitive Chemotherapy and Radiation Therapy
por: Pfister, Neil T., et al.
Publicado: (2022)

Facing Contrast-Enhancing Gliomas: Perfusion MRI in Grade III and Grade IV Gliomas according to Tumor Area
por: Di Stefano, Anna Luisa, et al.
Publicado: (2014)

DNA methylation, transcriptome and genetic copy number signatures of diffuse cerebral WHO grade II/III gliomas resolve cancer heterogeneity and development
por: Binder, H., et al.
Publicado: (2019)

BRAF, GNAQ, and GNA11 mutations and copy number in pediatric low-grade glioma
por: Laviv, Yosef, et al.
Publicado: (2012)

The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma
por: Carvalho, Diana, et al.
Publicado: (2014)

A phase II study of oral piritrexim in recurrent high-grade (III, IV) glioma.
por: Bleehen, N. M., et al.
Publicado: (1995)

Single institutional outcomes of whole brain radiotherapy for metastatic melanoma brain metastases
por: Jiang, Cecilia, et al.
Publicado: (2021)

Identification of Dysregulated Competitive Endogenous RNA Networks Driven by Copy Number Variations in Malignant Gliomas
por: Xu, Jinyuan, et al.
Publicado: (2019)

Systematic analysis of enhancer regulatory circuit perturbation driven by copy number variations in malignant glioma
por: Xiao, Jun, et al.
Publicado: (2021)

Oncogenic reg IV is a novel prognostic marker for glioma patient survival
por: Wang, Qi, et al.
Publicado: (2012)

Management and treatment recommendations for World Health Organization Grade III and IV gliomas
por: Altwairgi, Abdullah K., et al.
Publicado: (2017)

Efficacy of adenovirally expressed soluble TRAIL in human glioma organotypic slice culture and glioma xenografts
por: Liu, Y, et al.
Publicado: (2011)

Carrying out streamlined routine data analyses with reports for observational studies: introduction to a series of generic SAS (® )macros
por: Liu, Yuan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_fh4c90bejnikem2nupbva4sdml