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Potential synergic mechanism of Wutou-Gancao herb-pair by inhibiting efflux transporter P-glycoprotein

Wutou-Gancao herb-pair is extensively used to attenuate the toxicity and enhance the efficacy of aconite. In this study, potential synergic mechanism of the herb pair was investigated by utilizing multiple approaches. In silico and in vitro Caco-2 cell models were applied to study the potential bind...

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Detalles Bibliográficos
Autores principales: He, Yufei, Wei, Zihong, Xie, Ying, Yi, Xiulin, Zeng, Yong, Li, Yazhuo, Liu, Changxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7192969/
https://www.ncbi.nlm.nih.gov/pubmed/32373389
http://dx.doi.org/10.1016/j.jpha.2019.09.004