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Restricted Sequence Variation in Streptococcus pyogenes Penicillin Binding Proteins

A recent clinical report has linked Streptococcus pyogenes β-lactam antibiotic resistance to mutation in the penicillin binding protein (PBP) PBP2x. To determine whether this is an isolated case or reflects a broader prevalence of mutations that might confer reduced β-lactam susceptibility, we inves...

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Detalles Bibliográficos
Autores principales: Hayes, Andrew, Lacey, Jake A., Morris, Jacqueline M., Davies, Mark R., Tong, Steven Y. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193039/
https://www.ncbi.nlm.nih.gov/pubmed/32350098
http://dx.doi.org/10.1128/mSphere.00090-20