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Restricted Sequence Variation in Streptococcus pyogenes Penicillin Binding Proteins
A recent clinical report has linked Streptococcus pyogenes β-lactam antibiotic resistance to mutation in the penicillin binding protein (PBP) PBP2x. To determine whether this is an isolated case or reflects a broader prevalence of mutations that might confer reduced β-lactam susceptibility, we inves...
Autores principales: | Hayes, Andrew, Lacey, Jake A., Morris, Jacqueline M., Davies, Mark R., Tong, Steven Y. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193039/ https://www.ncbi.nlm.nih.gov/pubmed/32350098 http://dx.doi.org/10.1128/mSphere.00090-20 |
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