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Efficient Multiplex Gene Repression by CRISPR-dCpf1 in Corynebacterium glutamicum
Corynebacterium glutamicum is an important workhorse for industrial production of diversiform bioproducts. Multiplex control of metabolic pathway genes is crucial for maximizing biosynthesis of desired products. However, few tools for simultaneously regulating multiple genes in C. glutamicum have be...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193084/ https://www.ncbi.nlm.nih.gov/pubmed/32391351 http://dx.doi.org/10.3389/fbioe.2020.00357 |