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Production of Neutrophil Extracellular Traps Contributes to the Pathogenesis of Francisella tularemia

Francisella tularensis(Ft) is a highly virulent, intracellular Gram-negative bacterial pathogen. Acute Ft infection by aerosol route causes pneumonic tularemia, characterized by nodular hemorrhagic lesions, neutrophil-predominant influx, necrotic debris, fibrin deposition, and severe alveolitis. Ft...

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Detalles Bibliográficos
Autores principales: Pulavendran, Sivasami, Prasanthi, Maram, Ramachandran, Akhilesh, Grant, Rezabek, Snider, Timothy A., Chow, Vincent T. K., Malayer, Jerry R., Teluguakula, Narasaraju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193117/
https://www.ncbi.nlm.nih.gov/pubmed/32391009
http://dx.doi.org/10.3389/fimmu.2020.00679