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Lipoprotein‐Like Nanoparticle Carrying Small Interfering RNA Against Spalt‐Like Transcription Factor 4 Effectively Targets Hepatocellular Carcinoma Cells and Decreases Tumor Burden

Patients with advanced hepatocellular carcinoma (HCC) are often unable to tolerate chemotherapy due to liver dysfunction in the setting of cirrhosis. We investigate high‐density lipoprotein (HDL)‐mimicking peptide phospholipid scaffold (HPPS), which are nanoparticles that capitalize on normal lipopr...

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Detalles Bibliográficos
Autores principales: Cruz, William, Huang, Huang, Barber, Brian, Pasini, Elisa, Ding, Lili, Zheng, Gang, Chen, Juan, Bhat, Mamatha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193129/
https://www.ncbi.nlm.nih.gov/pubmed/32363325
http://dx.doi.org/10.1002/hep4.1493