Iron overload inhibits self‐renewal of human pluripotent stem cells via DNA damage and generation of reactive oxygen species

Iron overload affects the cell cycle of various cell types, but the effect of iron overload on human pluripotent stem cells has not yet been reported. Here, we show that the proliferation capacities of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) were signific...

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Detalles Bibliográficos
Autores principales: Han, Zhenbo, Xu, Zihang, Chen, Lei, Ye, Danyu, Yu, Yang, Zhang, Ying, Cao, Yang, Djibril, Bamba, Guo, Xiaofei, Gao, Xinlu, Zhang, Wenwen, Yu, Meixi, Liu, Shenzhen, Yan, Gege, Jin, Mengyu, Huang, Qi, Wang, Xiuxiu, Hua, Bingjie, Feng, Chao, Yang, Fan, Ma, Wenya, Liu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193162/
https://www.ncbi.nlm.nih.gov/pubmed/32053740
http://dx.doi.org/10.1002/2211-5463.12811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193162/
https://www.ncbi.nlm.nih.gov/pubmed/32053740
http://dx.doi.org/10.1002/2211-5463.12811

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