Hypoxia potentiates the capacity of melanoma cells to evade cisplatin and doxorubicin cytotoxicity via glycolytic shift

The hypoxic environment within solid tumors impedes the efficacy of chemotherapeutic treatments. Here, we demonstrate that hypoxia augments the capacity of melanoma cells to withstand cisplatin and doxorubicin cytotoxicity. We show that B16F10 cells derived from spontaneously formed melanoma and YUM...

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Detalles Bibliográficos
Autores principales: Zhuo, Ming, Gorgun, Falih M., Tyler, Douglas S., Englander, Ella W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193165/
https://www.ncbi.nlm.nih.gov/pubmed/32134564
http://dx.doi.org/10.1002/2211-5463.12830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7193165/
https://www.ncbi.nlm.nih.gov/pubmed/32134564
http://dx.doi.org/10.1002/2211-5463.12830

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